INTRODUCTION
Anxiety is a response to an unclear and ambiguous threat—an unpleasant feeling of apprehension and distressing fear anticipating an unspecified danger. Marx and Marx and leader, through a review of 22 studies in this field, estimated that approximately 3% of the general population experiences anxiety disorders (Moghadamipour, 1401).
Elevated anxiety levels during pregnancy not only increase the risk of depression, anxiety, and reduced milk production and secretion during the postpartum period but also lead to irritability, excessive crying, unstable conditions, and even impaired mental development in children by the age of two (Bowers et al., 2001). Other complications of such anxiety states may include preterm birth, low birth weight, and low Apgar scores at delivery. Moreover, the combination of depression and anxiety has been indicated to exert the most significant effect on the likelihood of preterm birth, far exceeding the impact of depression alone (Feld et al., 2010).
METHODS
The present quasi-experimental study employed a pretest-posttest design with a control group and a one-month follow-up period. The statistical population consisted of all pregnant women in Neyshabur City, Iran, who visited healthcare centers during the last three months of 2024. A sample of 45 participants was selected via convenience sampling and, after providing informed consent, was divided into two experimental groups and one control group (15 individuals per group).
Inclusion criteria involved informed consent, Iranian nationality and residency in Neyshabur, first-time pregnancy, maternal age between 18 and 30 years, singleton pregnancy, gestational age of 20–28 weeks, literacy, ability to perform 20 minutes of daily exercise, absence of congenital or genetic disorders, no acute psychiatric conditions, and no use of psychotropic medications. In addition, exclusion criteria involved pregnancy-related complications (history of miscarriage, bleeding, placenta previa, eclampsia), concurrent or prior use of yoga, psychotherapy, Pilates, meditation, etc., and history of stimulant or psychotropic drug use (e.g., sedatives, anxiolytics). Additionally, pregnant women with medical conditions or pregnancy disorders (severe acute/chronic illnesses harming the pregnancy), risk of preterm birth, confirmed fetal abnormalities, maternal cognitive/motor impairments, or absence from more than one session, non-completion of >10% of therapeutic tasks, exposure to distressing events (e.g., bereavement, family conflicts, migration), or non-compliance with questionnaire completion at pretest, posttest, or follow-up stages were excluded.
The intervention groups received Jacobson’s Progressive Muscle Relaxation (PMR) therapy (4 sessions) and Jon Kabat-Zinn’s Mindfulness-Based Stress Reduction (MBSR) therapy (eight sessions, 90 minutes each, twice weekly). Data were collected using the Vandenberg Pregnancy Anxiety Scale and analyzed via repeated-measures ANOVA.
RESULTS
The results indicated a significant difference between experimental and control groups; both therapies reduced pregnancy-related anxiety scores in primiparous women (p<0.05). Furthermore, MBSR demonstrated superior efficacy compared to PMR in alleviating pregnancy-related anxiety (p<0.05).
Table 1. Analysis of variance (ANOVA) results for pregnancy-related fear components.
| Source of Variation |
Variable |
Sum of Squares |
df |
Mean Square |
F-value |
Sig. (p) |
| Group |
Fear of Childbirth |
79.326 |
1 |
79.326 |
7.86 |
0.06 |
| Group |
Fear of Delivering a Disabled Child |
146.934 |
1 |
146.934 |
7.73 |
0.11 |
| Fear of Changes in Marital Relationships |
264.011 |
1 |
264.011 |
4.72 |
0.12 |
| Fear of Mood Changes |
157.334 |
1 |
157.334 |
8.76 |
0.10 |
| Self-Centered Fear |
134.567 |
1 |
134.567 |
9.87 |
0.06 |
| Error |
Fear of Childbirth |
255.722 |
28 |
9.132 |
– |
– |
| Fear of Delivering a Disabled Child |
556.322 |
28 |
19.765 |
– |
– |
| Fear of Changes in Marital Relationships |
140.111 |
28 |
50.040 |
– |
– |
| Fear of Mood Changes |
578.311 |
28 |
20.654 |
– |
– |
| Self-Centered Fear |
429.569 |
28 |
15.245 |
– |
– |
Table 1 presents the between-subjects test results for mean pregnancy-related anxiety scores in PMR and MBSR groups. The F-values for all anxiety components were statistically significant (p<0.05).
CONCLUSION
PMR reduces cortisol levels through physiological pathways, inducing relaxation by decreasing sympathetic nervous system activity and enhancing parasympathetic activity. It stabilizes the autonomic nervous system by regulating heart rate and blood pressure. Psychologically, PMR employs mechanisms like cognitive distraction and self-efficacy to reduce feelings of helplessness and anxiety.
The MBSR programs mitigate pregnancy-related anxiety in primiparous women through psychological mechanisms, such as reducing rumination, enhancing prenatal attachment, promoting emotional acceptance, and boosting self-efficacy. This intervention is particularly beneficial for high-risk women or those with a history of anxiety.
Findings revealed that both PMR and MBSR effectively reduced anxiety in primiparous women, though MBSR exhibited higher efficacy. These results are applicable in clinical settings such as gynecology clinics, pregnancy counseling centers, and even online programs.
Ethical Considerations
Compliance with ethical guidelines
Informed consent was obtained from all participants. The study’s ethical code (IR.IAU.NEYSHABUR.REC.1403.054) was approved by the Ethics Committee of the Islamic Azad University of Neyshabur Branch, Iran (IRCT code: IRCT20241127063881N1).
Funding
There is no funding support.
Authors' Contributions
First author: Supervised the second author and served as advisor and analyst.
Second author: Conducted research, data collection, and manuscript drafting.
Conflict of Interest
The authors declared no conflict of interest.
Acknowledgments
We are grateful to all the people for their scientific consultation in this research.