Introduction : Because Premenstrual Syndrome (PMS) leads to suicide, familial problem, interpersonal and job disorders in affected life and has direct and indirect effects on society so, removing this problem has been emphasized.
The object of this study is determining the effect of magnesium and placebo on premenstrual syndrome severity in the affected persons that go to medical-health centers of Esfahan University of medical sciences in 1388-89.
Methods: The participants of this essay were placed randomly in intervention or control group. The place of essay was 10 medical-health centers of Esfahan city and the duration of this study will be four month. For confirmation of recognition, persons completed daily rating form in their home for two month, then they randomly placed in one of two groups (magnesium or placebo) and drug intervention was done on them and the results was comprised.
Results: After statistical analyses, the results were as follow: The average of PMS score in two groups decreased after intervention in compare to before it and it was significantly with P-value less than 0/05 ( P <0/05) ,but this deduction in magnesium group was more than placebo group.( P <0/05)
Conclusions: The findings of this study totally showed that magnesium drug has more effect than placebo on premenstrual syndrome.
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