RT - Journal Article T1 - Investigating the Effect of Chelidonium majus Alcoholic Extract on Pituitary-Thyroid in Hypercholesterolemia Male Rats JF - CMJA YR - 2014 JO - CMJA VO - 4 IS - 1 UR - http://cmja.arakmu.ac.ir/article-1-229-en.html SP - 757 EP - 765 K1 - Chelidonium majus K1 - Thyroid K1 - Cholesterol K1 - Rat . AB -   Introduction: The aim of the present study is to evaluate the effect of alcoholic extract of Chelidonium majus concentration of cholesterol and thyroid hormone levels in the male rats having hypercholesterolemia.   Methods: In this study, 40 male Wistar rats were divided into five groups of control group (n=8) with normal diet, observing group with fat dietary, and three experimental groups receiving the same fat diet plus ethanol extract of the Chelidonium majus plant of 100, 200, 300 (mg/kg). After this period (21 days) blood samples were collected and after measuring the amount of thyroid hormones of T3, T4, TSH and also the amount of cholesterol, the data were analyzed by using SPSS software , ANOVA and t-test.   Results: There was a significant increase in the amount of cholesterol, T3 a nd T4 serum level in observation group comparing with control group (P LA eng UL http://cmja.arakmu.ac.ir/article-1-229-en.html M3 ER -