TY - JOUR T1 - The effect of aerobic training with coriander seed extract on lipoprotein A-1, Lipid Profile and Insulin Resistance in streptozotocin-induced diabetic rats TT - اثر یک دوره تمرین هوازی همراه با مصرف عصارۀ دانۀ گشنیز بر لیپوپروتئین A-1 سرمی، نیم‌رخ لیپیدی و مقاومت به انسولین در موش‌های صحرایی نر دیابتی با استرپتوزوسین JF - CMJA JO - CMJA VL - 7 IS - 3 UR - http://cmja.arakmu.ac.ir/article-1-439-en.html Y1 - 2017 SP - 1989 EP - 2000 KW - Aerobic training KW - Diabetes KW - Coriander seed extract KW - apoA-1 KW - Lipid profile N2 - Introduction: The aim of this study was to investigate the effect of aerobic training with coriander seed extract on apoA-1, Lipid Profile and Insulin Resistance in streptozotocin-induced diabetic rats. Methods: 40 diabetic male Wistar rats with the average age of 12 weeks and weight 130 ± 10 g were randomly divided into four groups: control, extract, training and training-extract. Diabetes was induced in rats with a single injection of streptozotocin-induced in a dose of 60 mg/kg of body weight. High glucose levels in 250 mg/dl defined as diabetic criteria. Extract administered orally 150 mg per kilogram of body weight per day. The program training was included six weeks of aerobic exercise, 5 times a week with 50 to 55 percent of maximal oxygen consumption. Data were analyzed with using of one-way ANOVA and Tukey test at α<0.05. Results: The results showed that aerobic training with coriander seed extract significantly affect serum apoA-1 (p=0.000) and glucose (p=0.002). However, it had no significant effect on insulin (p=0.656) and HOMA-IR (p=0.458). Also, aerobic training followed by coriander seed extract had a significant effect on triglyceride (p=0.007), total cholesterol (p=0.029), LDL (p=0.012) and HDL (p=0.000). Conclusion: It seems that regular aerobic exercise and coriander seed extract had beneficial effects on markers of cardiovascular risk in Diabetes and it can probably control some factors related to cardiovascular diseases. M3 ER -