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Volume 15, Issue 3 (12-2025)
cmja 2025, 15(3): 0-0 |
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bahram Z, pourvaghar M J, bahram M E. Effect of Eight Weeks of High-Intensity Circuit Training (HICT) Combined with Olive Leaf Extract Consumption on Serum Levels of Galectin-3, Interleukin-18, and Fasting Glucose in Obese Elderly Women. cmja 2025; 15 (3)
URL: http://cmja.arakmu.ac.ir/article-1-1053-en.html
URL: http://cmja.arakmu.ac.ir/article-1-1053-en.html
1- Master's Student in Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.
2- Associate Professor of Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran. ,vaghar@kashanu.ac.ir
3- PhD in Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.
2- Associate Professor of Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran. ,
3- PhD in Exercise Physiology, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.
Abstract: (18 Views)
Introduction: Galectin-3 and interleukin-18 (IL-18) are considered to be effective factors in age-related metabolic disorders and obesity, and their response to exercise training in elderly obese women is not well understood. The present study aimed to investigate the effect of 8 weeks of high-intensity circuit training (HICT) training combined with olive leaf extract consumption on serum levels of galectin-3, IL-18, and fasting glucose in elderly obese women.
Method: In this quasi-experimental study, 40 elderly obese women were selected as samples, with written and informed consent obtained, and were randomly assigned to four groups: placebo, supplement, exercise, and supplement + exercise (10 participants in each group). The supplement + exercise, as well as exercise groups, performed HICT training for eight weeks and three sessions per week for 45 to 60 minutes. The supplement + exercise, supplement, and placebo groups consumed one 125 mg capsule of olive leaf extract and a placebo after lunch for eight weeks. Before and after the test, blood samples were taken from all four groups. Data analysis was performed using a one-way ANOVA test and Tukey's post hoc test, as well as a paired t-test, at a significance level of P<0.05.
Results: The intergroup results showed a significant decrease in the values of galectin-3, IL-18, and fasting glucose in the studied groups (P=0.001). The results of Tukey's post hoc test showed a significant difference in the variables of galectin-3 and IL-18 between the exercise group and the supplement and control groups, as well as between the exercise + supplement group and the supplement and control groups. There was a significant difference in the glucose index between the exercise group and the exercise + supplement and control groups. Moreover, the most significant decrease was observed in the exercise + supplement group.
Conclusion: Although HICT training alone can be effective in reducing galectin-3, IL-18, and fasting glucose, prescribing HICT training along with olive leaf extract has a synergistic effect in improving pro-inflammatory markers and fasting glucose.
Method: In this quasi-experimental study, 40 elderly obese women were selected as samples, with written and informed consent obtained, and were randomly assigned to four groups: placebo, supplement, exercise, and supplement + exercise (10 participants in each group). The supplement + exercise, as well as exercise groups, performed HICT training for eight weeks and three sessions per week for 45 to 60 minutes. The supplement + exercise, supplement, and placebo groups consumed one 125 mg capsule of olive leaf extract and a placebo after lunch for eight weeks. Before and after the test, blood samples were taken from all four groups. Data analysis was performed using a one-way ANOVA test and Tukey's post hoc test, as well as a paired t-test, at a significance level of P<0.05.
Results: The intergroup results showed a significant decrease in the values of galectin-3, IL-18, and fasting glucose in the studied groups (P=0.001). The results of Tukey's post hoc test showed a significant difference in the variables of galectin-3 and IL-18 between the exercise group and the supplement and control groups, as well as between the exercise + supplement group and the supplement and control groups. There was a significant difference in the glucose index between the exercise group and the exercise + supplement and control groups. Moreover, the most significant decrease was observed in the exercise + supplement group.
Conclusion: Although HICT training alone can be effective in reducing galectin-3, IL-18, and fasting glucose, prescribing HICT training along with olive leaf extract has a synergistic effect in improving pro-inflammatory markers and fasting glucose.
Type of Study: Research |
Subject:
Physiology
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