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Volume 3, Issue 1 (6-2013)                   cmja 2013, 3(1): 418-428 | Back to browse issues page

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malekhosseini A, Ghaffarzadegan R, Alizadeh S A, , Ghaffarzadegan R R, Haji Agaei R, Ahmadlou M. Effect of aloe vera gel, compared to 1% silver sulfadiazine cream on second-degree burn wound healing. cmja. 2013; 3 (1) :418-428
URL: http://cmja.arakmu.ac.ir/article-1-136-en.html
1- arak medical university
2- arak medical university , Iran ghafarzadegan@arakmu.ac.ir
3- Institute of Medicinal Plants Jahad University, Karaj, Iran
4- University Jihad, Karaj, Iran
Abstract:   (21548 Views)

  Introduction : Aloe vera has been traditionally used for burn healing but clinical evidence remains unclear. Today, because of fewer side effects and less expensive medicinal plants , their use is increasing.This study compared the effects of silver sulfadiazin 1% and Aloe vera gel dressing on burn wound healing.

  Methods: This randomized, controlled trial in vali Asr Hospital of Arak city was done. The patients were randomly divided into two equal groups group I (n = 32): treated topically with of silver sulfadiazin 1% cream control group and group II (n = 32): patients treated topically with Aloe vera gel . By using the Wound assessment tool bats - Jensen examined the wound healing process. analysis of variance REMANOVA was used to evaluate the differences of wound healing parameters between treated and control groups. All analyses were performed using SPSS 17.0 (SPSS Inc., Chicago , IL, USA). A P-value lower than 0.05 was considered significant.

  Results: Experimental group mean improvement in the baseline 30/515 with a standard deviation of 0/ 316 , and the fifteenth day of the 13/303 SD 0/516 AKA controls at baseline 31/219 with a standard deviation of 0/ 321 , and the fifteenth day of the 19/188 with a standard deviation of 0/ 524dropped . There was a significant difference between groups on the fifteenth day ( P = 0/000, F =467/602).

  Conclusion : Due to the complication of silver sulfa Dyazyn cream 1% relative inhibition of epithelialization and wound discoloration in the area, Aloe Vera Gel can be a good substitute for wound healing.


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