Introduction: One of the major complications of hemodialysis patients is restless legs syndrome (RLS). Therefore, interventions are essential to its improvement. This study aimed to determine the effect of massage with glycerin oil on RLS in hemodyalysis patients.

Methods: The present study is a randomized clinical trial in chronic renal failure patients undergoing hemodyalysis in Kamkar hospital, Ghom, Iran, 2014. Seventeen patients with RLS were selected after obtaining the informed consent by continuous method and randomly assigned into 2 groups. The intervention group received effleurage massage with glycerin oil, and the control group received the routine care of hemodyalysis ward. Data were collected by RLS questionnaire and analyzed by descriptive and analytical (Exact Fisher, dependent and independent t-test) statistic in Spss v16.

Results: No significant difference found in RLS score between intervention (24.09±5.34) and control (22.9±4.38) groups in beginning of study. While mean of score RLS had significant decrease in massage with glycerin oil group (9.54±4.64) in comparison with the control group (23.23±4.52) (p=0/0001).

Conclusion: it is recommended to use effleurage massage with glycerin oil as a complementary therapy  to decrease the RLS in hemodyalysis patients.