Volume 10, Issue 3 (12-2020)
cmja 2020, 10(3): 244-257 |
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1- Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.
2- Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Razi University, Kermanshah, Iran. , vahidtadibi@razi.ac.ir
3- Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Razi University, Kermanshah, Iran.
2- Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Razi University, Kermanshah, Iran. , vahidtadibi@razi.ac.ir
3- Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Razi University, Kermanshah, Iran.
Abstract: (2882 Views)
Objective: Diabetes is a chronic disease associated with a wide range of liver diseases. The levels of liver enzymes such as Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) are changed following a liver disease The purpose of this study is to investigate the effect of aerobic exercise combined with Stevia extract supplementation on the levels of ALT and AST enzymes in diabetic rats.
Methods: In this experimental study, 40 males wistar rats weighing 150-220 g were used. Animals were randomly divided into five groups; healthy control , diabetic control, diabetic + exercise, diabetic + stevia, and diabetic + exercise + stevia. The extract was administered by oral gavage for 6 weeks. The aerobic exercise program was performed for six weeks, 5 days per week. At the end of the intervention, blood samples were collected from the heart of rats to measure the levels of ALT and AST. Data were analyzed by one-way ANOVA and Tukey’s post hoc test.
Results: The levels of ALT and AST enzymes decreased significantly in all experimental groups compared to diabetic control group (P<0.05).
Conclusion: Aerobic exercise combined with stevia extract supplementation can improve the liver function in streptozotocin-induced diabetic rats
Methods: In this experimental study, 40 males wistar rats weighing 150-220 g were used. Animals were randomly divided into five groups; healthy control , diabetic control, diabetic + exercise, diabetic + stevia, and diabetic + exercise + stevia. The extract was administered by oral gavage for 6 weeks. The aerobic exercise program was performed for six weeks, 5 days per week. At the end of the intervention, blood samples were collected from the heart of rats to measure the levels of ALT and AST. Data were analyzed by one-way ANOVA and Tukey’s post hoc test.
Results: The levels of ALT and AST enzymes decreased significantly in all experimental groups compared to diabetic control group (P<0.05).
Conclusion: Aerobic exercise combined with stevia extract supplementation can improve the liver function in streptozotocin-induced diabetic rats
Type of Study: Research |
Subject:
Medicinal Plants
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