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Showing 2 results for Insulin Resistance Index

B Ghorbanian, H Mohammadi, K Azali,
Volume 7, Issue 1 (6-2017)
Abstract

Introduction: Rhus coriaria. L (Rc.L) as an herbal remedy used in traditional medicine. The purpose of this study was to investigate the effects of 10-weeks aerobic training with Rhus coriaria. L supplementation on total antioxidant capacity (TAC), insulin resistance and anthropometric indices in women with type 2 diabetes.

Methods: This quasi-experimental study was performed in 2016 on 40 type II diabetic women )40 to 60 yr (of Ajabshir city that volunteered and randomly assigned into 1-Rc.L supplement, 2- exercise, 3- Rc.L supplement+exercise and 4- control groups. Exercise protocol was aerobics and walking activity for 10 weeks (3d/wk, 40 to 60 min/d with 45-60% HRRmax intensity). Subjects in groups 1and 3 received 3 grams of Rc.L powder daily. Fasting blood samples were collected in pre and post-test following 48 hours of inactivity and not consumption of Rc.L and 12 hours of fasting. Data were analyzed by t-test, ANOVA and LSD Statistical tests at significance level of p<0.05.

Results: TAC increased significantly after 10 weeks in Rc.L supplement group and insulin resistance index significantly decreased in 1, 2 and 3 groups. Also anthropometric measures (weight, body mass index & etc) were significantly decreased in 1, 2 and 3 groups (p<0.05).

Conclusion: Given that Rc.L supplementation along aerobics and walking activity, has favorable effects on total antioxidant capacity, insulin sensitivity, blood glucose and anthropometric indices in people with type 2 diabetes. So it can be used as a complementary therapy along with medications to control diabetes and prevent its complications.


Mohammad Parastesh, Abbas Saremi, Meisam Ebadianejad,
Volume 9, Issue 3 (12-2019)
Abstract

Objective The aim of this study was to investigate the effect of supplementation with chromium picolinate combined with resistance training on the serum level of liver enzymes and insulin resistance index (HOMA-IR) in male patients with Type 2 Diabetes (T2D).
Methods In this study, participants were 30 male patients with T2D (Mean±SD weight: 75.1±6.3 kg and BMI= 26.1±2.3 kg/m2). They were divided into three groups (two experimental and one control). In addition to resistance training for 8 weeks, experimental groups consumed 400-mg chromium picolinate daily and placebo. Serum levels of liver enzymes, insulin and glucose were measured before and after the training period. Data were analyzed using one-way ACNOVA and Bonferroni correction test (P<0.05).
Results Both resistance training combined with chromium picolinate supplementation (P=0.04) and resistance training with placebo (P=0.11) significantly reduced HOMA-IR compared to the control group. They both also resulted in a significant decrease in Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) enzymes level compared to the diabetic control group (P=0.01). Resistance training along with chromium picolinate supplementation (P=0.01) significantly reduced the waist-hip ratio (P=0.04) and fat percentage (P=0.01) compared to controls.
Conclusion training combined with chromium picolinate supplementation is more effective in improving the liver enzymes level in T2D patients.




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