INTRODUCTION
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age (Mohammadi et al. 2020). In Iran, the prevalence of PCOS has been estimated in various studies, based on different criteria, to range between 4% and 20% (Pourhoseini et al. 2021). The main complications of this condition during adolescence include amenorrhea, oligomenorrhea, obesity, and acne. In reproductive ages, the primary complaints are infertility and irregular ovulation. This syndrome is a major cause of infertility, with 44.6% of married women with PCOS reporting infertility issues (Rohani et al. 2017).
Treatment for PCOS includes managing hirsutism, addressing infertility using medications, such as clomiphene, metformin, and dexamethasone—each with its own side effects—and general treatments like weight loss. While these approaches may slow the progression of the syndrome, they do not provide a definitive cure (Saman et al. 2015). Despite extensive efforts by researchers worldwide, no drug approved by the U.S. Food and Drug Administration (FDA) has been reported for the treatment of PCOS (Saei et al.2021).
Efforts to find newer, less harmful, easier, more cost-effective, and more efficient treatment methods continue. There is a growing trend toward integrating complementary medicine with conventional medicine, creating integrative medicine. Ziomkiwiz and colleagues found a connection between Mizaj and women’s reproductive activity and ovarian hormones. Similarly, Sohrabvand et al. observed that cold Mizaj is more prevalent among infertile women (Nabiuni, 2013).
The research revealed no prior studies examining the relationship between personal Mizaj and uterine Mizaj in women with PCOS. Considering the complications of PCOS and the importance of its treatment, especially through non-drug methods, the present study was conducted in 2021 to determine the personal and uterine Mizaj of women with PCOS attending comprehensive health centers in Nahavand City, Iran.

METHODS
In this descriptive cross-sectional study, 96 women diagnosed with PCOS who attended comprehensive health centers in Nahavand city in 2021 were examined. Inclusion criteria included being aged in the range of 20-40 years. Exclusion criteria included having other endocrine or chronic diseases, long-term use of hormonal or chemical drugs that could interfere with Mizaj, and suffering from recognized mental disorders.
For sampling, coordination was established with midwives from 18 comprehensive health centers in Nahavand city. They were asked to invite women who had been diagnosed with PCOS by a gynecologist during the week and were willing to participate in the study to attend the center on a specific day. The researcher assessed these women’s Mizaj. For data collection, necessary coordination was carried out with physicians and healthcare staff, and before sampling, the study objectives were explained to participants. Then, demographic and fertility information forms were completed.
The room temperature was set to 24°C, and participants were given a personal Mizaj questionnaire to complete. Additionally, the uterine Mizaj questionnaire by Tannaz et al.  was completed. Participants’ weight and height were measured using a Seca bascule scale (made in Germany), which also had height gauge.
The temperature of the pubic region, buttocks, and forehead was measured using an infrared thermometer (model 1D1AET-R) manufactured in China. Internal body temperature was also measured using a mercury thermometer through the vagina, and the data for each study participant were recorded.
Collected data were entered into the SPSS (version 23) software. The Spearman correlation coefficient was used to assess the correlation between personal Mizaj scores and uterine Mizaj.

RESULTS
The age range of the participants was 20 to 39 years, with a mean age of 29.76 years and a standard deviation of 5.44. The waist-to-hip ratio ranged from 0.67 to 0.85, with a mean of 0.77. All participants were residents of Nahavand County. Among the study participants, 2.1% (n=2) were illiterate, and 72.9% (n=70) were housewives. Secondary infertility was observed in 3.8% (n=5) of individuals, and 44.8% (n=43) had no history of childbirth. In addition, natural delivery was reported by 25% (n=24).
Regarding contraceptive methods, 49% (n=47) used natural methods, while 15.6% (n=15) did not use any contraception. Irregular menstruation was reported by 45.8% (n=44).
The most common single personal Mizaj was cold (78.1%, n=75) in terms of cold and warm, and wet Mizaj (52.1%, n=50) in terms of wet and dry. Among the compound Mizaj, the most common was cold and wet Mizaj (42.7%, n=41).
For uterine Mizaj, 81.3% (n=78) exhibited a cold Mizaj, and 63.5% (n=61) had a wet uterine Mizaj. The most frequent compound uterine Mizajwas cold and wet (56.25%, n=54).
The correlation between personal and uterine Mizaj was statistically significant (r=0.44, P<0.001).

CONCLUSION
The results indicated that the most common single Mizaj in the uterus was cold among cold and hot, and wet Mizaj among wet and dry. Among compound Mizaj, the most common personal and uterine Mizaj was cold and wet.