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1- MSc of Exercise Physiology, Faculty of Sport Sciences, Bu-Ali Sina University, Hamadan, Iran
2- Professor of Exercise Physiology, Faculty of Sport Sciences, Bu-Ali Sina University, Hamadan, Iran ,a.heidarianpour@basu.ac.ir
3- Department of Physical Education, Technical and Vocational University (TVU), Tehran, Iran
2- Professor of Exercise Physiology, Faculty of Sport Sciences, Bu-Ali Sina University, Hamadan, Iran ,
3- Department of Physical Education, Technical and Vocational University (TVU), Tehran, Iran
Abstract: (20 Views)
Introduction: Alzheimer's disease is a progressive neuropsychiatric disorder that mainly affects cognitive function and memory. Many studies have been conducted on exercise, Alzheimer's, herbs, and Alzheimer's, but no study has been conducted on the use of sumac and simultaneous exercise, and the aim of this study is to investigate the effect of endurance, strength, and combined exercise along with sumac consumption on the pain threshold of Alzheimer's mice.
Materials and Methods: In this semi-experimental study, 70 male Vistar Rats were selected with an average weight of 20 ± 200 g. For Alzheimer's induction, 8 mg/kg of trimethyltinchloride (TMT) were dissolved with normal saline and injected into the peritoneum. Then, the rats were randomly divided into 10 groups: control, Alzheimer's, Alzheimer's, Alzheimer's, Alzheimer's, Alzheimer's, resistant, Alzheimer's, combined, Alzheimer's, swimming, Alzheimer's, resistant, combined Alzheimer's. The rats underwent endurance training in a swimming pool for 12 weeks, with five sessions per week. The resistance training involved climbing a ladder with weights attached to their tails. In addition, for strength training, the combined program was practiced two days per week, and for endurance training, they practiced three days a week. Their pain threshold was checked by two teleflik tests, the hotplate after 12 weeks. For descriptive statistics, mean and standard deviation were used. For inferential statistics and research hypotheses, the one-strain anvai test was used and for intra-group comparisons of the toki post-tracking test. Statistical analyses were performed using SPSS software (version 29).
Results: Based on the findings of the present research, 12 weeks of strength, endurance, and combined exercise with the use of sumac, compared to the control group, increased the pain threshold of rats with Alzheimer's diease in the endurance and combined group (p=0.001); however, it was not significant in the power group (p=0.62). The increase in the pain threshold in the sumac intake group was also not statistically significant.
Conclusion: Combined exercise (endurance + resistance) along with the use of sumac had the highest effect on increasing the pain threshold in Alzheimer's mice, possibly due to the doubling of the effect of exercise and sumac simultaneously.
Materials and Methods: In this semi-experimental study, 70 male Vistar Rats were selected with an average weight of 20 ± 200 g. For Alzheimer's induction, 8 mg/kg of trimethyltinchloride (TMT) were dissolved with normal saline and injected into the peritoneum. Then, the rats were randomly divided into 10 groups: control, Alzheimer's, Alzheimer's, Alzheimer's, Alzheimer's, Alzheimer's, resistant, Alzheimer's, combined, Alzheimer's, swimming, Alzheimer's, resistant, combined Alzheimer's. The rats underwent endurance training in a swimming pool for 12 weeks, with five sessions per week. The resistance training involved climbing a ladder with weights attached to their tails. In addition, for strength training, the combined program was practiced two days per week, and for endurance training, they practiced three days a week. Their pain threshold was checked by two teleflik tests, the hotplate after 12 weeks. For descriptive statistics, mean and standard deviation were used. For inferential statistics and research hypotheses, the one-strain anvai test was used and for intra-group comparisons of the toki post-tracking test. Statistical analyses were performed using SPSS software (version 29).
Results: Based on the findings of the present research, 12 weeks of strength, endurance, and combined exercise with the use of sumac, compared to the control group, increased the pain threshold of rats with Alzheimer's diease in the endurance and combined group (p=0.001); however, it was not significant in the power group (p=0.62). The increase in the pain threshold in the sumac intake group was also not statistically significant.
Conclusion: Combined exercise (endurance + resistance) along with the use of sumac had the highest effect on increasing the pain threshold in Alzheimer's mice, possibly due to the doubling of the effect of exercise and sumac simultaneously.
Type of Study: Research |
Subject:
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