Volume 6, Issue 1 (6-2016)                   cmja 2016, 6(1): 1432-1440 | Back to browse issues page

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asgari P, mahmoudi M, bahramnezhad F, mokhtari R, rafiei F. Investigating the Effect of Kelussia Odoratissima on the Rate of Improvement in Patients with Peptic Ulcer . cmja. 2016; 6 (1) :1432-1440
URL: http://cmja.arakmu.ac.ir/article-1-409-en.html
arak university of medical sciences , mahmodimokhtar85@gmail.com
Abstract:   (1951 Views)

Introduction: The studies on animal models have shown positive effects of Kelussia odoratissima on different health problem cases including digestive disorders. However, there has been no research on the effectiveness of Kelussia odoratissima on peptic ulcers in humans. In this study, "the effect of Kelussia odoratissima on the rate of improvement in patients with peptic ulcer" has been investigated.

Methods: The present study was a Randomized clinical trial which is done in March- September, 2015 in Amir Al-Momenin Hospital in Arak, Iran. The subjects were 60 patients with peptic ulcer, selected by simple random sampling and acquiring their informed consents. After taking written informed consent, they were divided into two groups randomly: the control group (administering prescribed medicines) and the intervention group (administering medicines along with Kelussia odoratissima powder). One month after intervention, the types of peptic ulcers were determined by follow-up endoscopy. Finally, the data was analyzed using SPSS v. 16 and statistical independent samples t-test and Fisher’s exact test.

Results: The two groups were homogenous in terms of demographic features. The findings showed that the groups were not significantly different regarding the type of peptic ulcers (p= 0.91) before intervention; but one month after intervention, the highest frequency in the control group was related to the ulcers Type II and III, and the lowest frequency to the ulcers Type I, while the highest frequency in the intervention group was related to the ulcers Type I and the lowest frequency to the ulcers Type III and higher. Accordingly, Fisher’s exact test showed a significant difference between the two groups (p=0.008).

Conclusion: Given the results of the present study, it seems that administering Kelussia odoratissima powder along with the medicines effective for treating stomach ulcers has a positive effect on patients with peptic ulcer.

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Type of Study: Research | Subject: Medicinal Plants

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