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Volume 8, Issue 3 (12-2018)                   cmja 2018, 8(3): 2374-2413 | Back to browse issues page

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Mirjalili A. Bioactive compounds and their Mechanism in anticancer plants listed in flora of Iran. cmja. 2018; 8 (3) :2374-2413
URL: http://cmja.arakmu.ac.ir/article-1-512-en.html
Plant Production Department, Imam Khomeini Higher Education Center, Agriculture Research, Education and Extension Organization, Tehran, Iran. , abmirjalili@gmail.com
Abstract:   (1444 Views)

Introduction: Continued search for safer and more effective phytochemicals to be used in chemotherapy is ultimate goal of pharmacologists. Cancer chemoprevention with natural phytochemical compounds is an emerging strategy to prevent, impede, delay, or cure cancer. This study aimed to review the research conducted on anticancer ingredients extracted from native plant species of Iran.
Methods: The study was conducted by searching scientific documents published in Google scholar, PubMed and ScienceDirect since 2010. The keyword was “anticancer Iranian medicinal plants” and the phrases “bioactive compounds” and “mechanism” limited the scope of search. The papers studying native plant species of Iran were selected.
Results: Out of 15900 records reported in Google scholar, 13700 have been published after 2010, which were selectively reviewed. Searching PubMed and ScienceDirect provided 10 and 233 reports, respectively. Totally, searching the literature showed that two species of algae, six species of gymnosperms and 177 species of angiosperms form Iran have been reported as anticancer plants.
Conclutions: The results showed that 185 species, including algae and higher plants grown in Iran, can be potentially used in cancer treatment and understanding the mechanism by which their bioactive compounds work could improve our understanding of cancer treatment methods.

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Type of Study: Research | Subject: Medicinal Plants

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