Background: Knee arthritis is a joint disease caused by the destruction of the underlying cartilage and bone. Common symptoms of this disease are stiffness and pain. Dry cupping and Iaraj Fiqra capsules are used in Persian medicine to treat knee arthritis. Therefore, the present study aimed to assess the effect of the Iaraj Fiqra capsule and dry cupping on arthritis and compare their effects.
Materials and Methods: This randomized, single-blind trial was conducted on 61 subjects aged 60 to 69 years old with knee osteoarthritis after obtaining informed consent. Patients were randomly assigned to two groups. One group received 500 mg/day of Iaraj Fiqra capsules for four weeks (n=31), and the other group received dry cupping on the knee for 10 min twice a week for four weeks (n=30). Patients completed the Knee Injury and Osteoarthritis Outcome Score questionnaire, which assessed five areas: pain, symptoms, daily activities, sports and recreation function, and knee-related quality of life, both before and after the study. Independent and paired t-tests, Fisher's exact test, and the Chi-square test were used to evaluate the data in GraphPad software (version 8).
Results: The results demonstrated that Iaraj Fiqra capsules and dry cupping for four weeks improved pain (Iaraj Fiqra capsule: before: 92.1±1.3 and after: 73.1±1.4, p=0.002, dry cupping: before: 96.6±2.3 and after: 83.0±3.1; P=0.02), symptoms (Iaraj Fiqra capsule: before: 84.12±3.1 and after: 73.23±1.5; P=0.005, dry cupping: before: 82.11±1.2 and after: 67.31±1.1; P=0.001), daily activities (Iaraj Fiqra capsule: before: 32.22±2.5 and after: 76.21±0.6; P=0.002, dry cupping: before: 34.15±1.4 and after: 72.12±1.2; P=0.001), sports performance (Iaraj Fiqra capsule: before: 92.1±1.3 and after: 73.1±1.4; P=0.002, dry cupping: before: 96.6±2.3 and after: 83.0±3.1; P=0.001,) and recreational (Iaraj Fiqra capsule: before: 24.21±1.2 and after: 68.11±0.5; P=0.002, dry cupping: before: 28.95±1.2 and after: 62.25±2.7; P=0.001), and knee-related quality of life scores (Iaraj Fiqra capsule: before: 31.11±0.6 and after: 82.32±11.4; P=0.002, dry cupping: before: 11.6±33.11 and after: 81.21±1.4; P=0.002). Furthermore, the results demonstrated that the pain score of patients improved significantly compared to the dry cupping group (P<0.05).
Conclusion: As evidenced by the obtained results, Iaraj Fiqra capsules and dry cupping can be used to improve the pain, symptoms, daily activities, sports and recreation function, and knee-related quality of life of individuals with knee osteoarthritis.