Heidarianpour A, Shamsholahi M, Naderi A, Rabiani Z. The Effect of 8 weeks of functional training with the oral intake of ginger powder on the levels of IL6 and IL10 in patients with knee osteoarthritis. cmja 2025; 15 (1)
URL:
http://cmja.arakmu.ac.ir/article-1-1030-en.html
1- Professor of Exercise physiology, Faculty of Sport sciences, Bu-Ali Sina university, Hamadan, Iran , a.heidarianpour@basu.ac.ir
2- MSc in Exercise physiology, Faculty of Sport sciences, Bu-Ali Sina university, Hamadan, Iran
3- Department of exercise and sport sciences, National University of skill(NUS), Tehran, Iran
4- MSc of Exercise physiology, Faculty of Sport sciences, Bu-Ali Sina university, Hamadan, Iran
Abstract: (64 Views)
Background and Objective: Osteoarthritis is one of the age-related inflammatory diseases. The integration of exercise programs and natural supplements, such as ginger, which possess anti-inflammatory properties, could help manage the symptoms of this disease. The present study aimed to assess the effect of ginger supplementation alongside functional exercises on inflammatory factor levels in patients with knee osteoarthritis.
Materials and Methods: In this experimental study, the subjects were patients with knee osteoarthritis who voluntarily participated in the study, consisting of 40 women aged 55-65 years with a mean weight of 75-85 kilograms. They were randomly assigned to four groups of 10 people: exercise, control, ginger, and exercise with ginger. The exercise program consisted of two parts: the first part included light exercises, and the second part entailed a combination of exercises. The training program was conducted for eight weeks, three times a week. Blood samples were taken 24 hours before and after the exercise program. For data analysis, the Shapiro-Wilk test was used to check for normality, and for comparison between groups, one-way ANOVA and Tukey's post-hoc test were employed using SPSS software (version 29).
Results: After eight weeks of intervention, there were significant reductions in the levels of interleukin 6 and interleukin 10 in the exercise group, the ginger supplement group, and the exercise+ginger supplement group compared to before the intervention (P=0.0001).
Conclusion: It seems that performing functional exercises for eight weeks along with consuming ginger powder can be effective in the mitigation of inflammatory factors associated with knee osteoarthritis.
Type of Study:
Research |
Subject:
Medicinal Plants