Introduction: angiography, lead to increase patient’s levels of anxiety. Multiple therapies are used to reduce anxiety. This study aims to investigate the effect of the pressure of (Yintang and shenmen) points on the patients’ anxiety before the coronary angiography.

Methods: This Single blind randomized controlled trial study was performed on 70 patients before angiography. After obtaining informed consent, patients were randomly assigned in intervention and control groups. Patients in the intervention group received pressure on Yintang and ear - Shenmen points for 10 minutes; one hour before angiography while patients in the control group received pressure in placebo points at the same time. Anxiety was measured by Spielberger questionnaire in 2 groups; 10 minutes before, 1 and 30 minutes after the intervention. Descriptive statistics, t-test, paired t-test and analysis of covariance were used to analyze.

Result: In the intervention group, the mean score of anxiety significantly decreased from 49.80 to 42.17 one minute after the intervention. In the control group, anxiety increased from 48.57 to 48.80. The observed differences were matched by age and Anxiety level before the intervention, was (p<0.001). In the intervention group, the mean score of anxiety decreased from 49.80 to 38.05, 30 minutes after the intervention while in the control group, the mean score of anxiety increased from 48.57 to 49.31. The difference observed between the intervention and control groups were matched by age and Anxiety level before the intervention, (p<0.001).

Conclusion: Simultaneous Acupressure on Yintang and auriculotherapy in Shenmen may reduce anxiety of patients before coronary angiography