Volume 5, Number 2 (9-2015)                   cmja 2015, 5(2): 1123-1132 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

jamilian M, hekmatpou D, jamilian H. Comparison of the effect of Ginger, Gabapentin , and ondansetron for prevention of nausea and vomiting after cesarean section by spinal anesthesia. cmja. 2015; 5 (2) :1123-1132
URL: http://cmja.arakmu.ac.ir/article-1-295-en.html

Assisstant Professor Arak University of Medical Sciences , mjamilian@arakmu.ac.ir
Abstract:   (1674 Views)

Introduction: Nausea and vomiting are among the most common complications of Caesarean section and may cause suture dehiscence, esophageal perforation, gastric aspiration, and delay in hospital discharge. The aim of this study was to compare the antiemetic effect of Ginger, Gabapentin, and Ondansetron for prevention of nausea and vomiting after cesarean section by spinal anesthesia.

Methods: This randomized, double-blind placebo controlled clinical trial was done on 208 women undergoing elective cesarean section. After taking written informed consents, they were divided into four equal groups. 300 mg Gabapentin, 8 mg Ondansetron, 1 gr Ginger, and placebo were administered to each group. Before performing spinal anesthesia and after the operation in recovery, and also in 2, 4, and 6 hours intervals after the surgery, nausea and vomiting were recorded based on a four point scale. Data was analyzed by SPSS 19 using one way ANOVA, independent t-test and Chi square.

Results: There were no significant differences among the four groups according to age, gravidity mothers` mean atrial pressure and heart rate before and during surgery, newborns` APGAR score and mothers` consciousness. Nausea and vomiting in Gabapentin (0.28±0.34), Ondansetron (0.28±0.25), and Ginger (0.27±0.85) groups were significantly less than placebo group (1±0.22) (p=0.01), whereas there were no significant differences among the three groups (p=0.05).

Conclusion: Using Gabapentin, Ondansetron and Ginger with the same antiemetic effect are appropriate for women undergoing cesarean section.

Full-Text [PDF 180 kb]   (733 Downloads)    
Type of Study: Research |

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Complementary Medicine Journal of faculty of Nursing & Midwifery

Designed & Developed by : Yektaweb