Introduction: The present study aims to assess the relative frequency use of complementary and alternative medicine (CAM) among the patients with Type 2 diabetes, during the prevalence of type 2 diabetes in Isfahan in 2013.

Methods: The study considers a descriptive-cross sectional study. Four hundred patients with type 2 diabetes were selected with improbable sampling. Data were collected by the method of interviewing and use of questionnaire after taking consent from patients and analyzed by SPSS20 Software.

Results: In CAM we have different approaches to manage the disease. In our study 85.8% of the patients with type 2 diabetes used at least one of CAM methods. The frequency of various CAM methods was included natural product (41.7%), Manipulative & Body based practices & Movement-based approaches (35.9%), Spiritual practices (34.1%), Practices of traditional healers (18.4%), Mind & body medicine (12.8%), Whole medical system (4.1%), other methods (2.6%) and Putative energy field (2.3%), respectively.

conclusion: Based on the obtained results, the majority of the patients with diabetes used CAM along with drug therapy. If the doctors want to consult their patients properly they will need more scientific data. In addition, the need for advance research for recognition of CAM effects is necessary in order to teach and manage blood sugar level better among the patients with Type 2 diabetes.