Introduction: delivery is a natural and painful phenomen .acupressure is one of the alternative methods for pain managment . . because of the side effects of drug using.the purpose of this study is to determine effect of acupressure for relief of labor pain in the first stage of labor is assesed. Methods :a single blind clinical trial designed for assessment of effect of acupressure on labor pain .sampling method was non randomized and available samples but samples divided randomize to two groups including65 persons as case group and 65 person as control group . acupressure conducted with cupping method . case group received BL32 and GB21 acupressure and control group received placebo p6 point acupressure for one minute in the start of every contraction in the first stage of labor . pain severity was measured by use of VAS tool and demographic characters was measured by questionnaire . softwaire of spss and Ttest was used for analysis . Results :findings indicated that mean of severity of pain difference between two groups before intervention was insignificantly with (p=0/019)but after intervention in the case group was more than control group significantly with (p=0/039). Conclusions : :results of this study showed that acupressure with above named method non effective on labor pain in examined women. Key words ::-acupressure –BL32– -GB21-labor pain