Introduction: Lipid disorders of the most important factors involved in the development and progression of cardiovascular lesions, The aim of this study was to evaluate the role and use of a combination of honey and apple cider vinegar on blood lipids in patients with hyperlipidemia is.

Methods: This study was clinical trial and its demonstrate in in Amiralmomenin and Vali- Asr hospital. 30 samples were selected that For one group before and after the intervention by ethical satisfaction. For subsequent investigations, levels of blood lipids are measured at the beginning of and 4 weeks after the intervention for the participants in groups using blood tests, in the intervention group administered one tablespoon each honey and apple vinegar in a glass containing 200cc water twice a day in addition to their usual lipid-lowering drugs. After 4 weeks, levels of blood lipids were measured in groups and were analyzed by SPSS v.20.

Results: after intervention, result shown that TG Min & Sd before 314.13(79.8) and after164.56(42.9), CHOL(Min & Sd before 256.8(58.13) and after137.7(31.26), LDL Min & Sd before 185.4(48.6) and after120.43(25.07), have significant difference with group, and HDL) Min & Sd before 43.30(10.6) and after64.03(16.1), increased after intervention.

Conclusion: This study demonstrated that a combination of honey and apple vinegar is very effective role in reducing bad fats and good fats increase in patients with high blood fat.